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Yiju Maiju as a new type of selective cholesterol absorption inhibitor, shows unique advantages in clinical blood lipid management.Its unique mechanism is that Yibanmubu is activated by inhibiting the bristles of the small intestinal mucosa NPC1L1 transport, reducing the absorption of cholesterol and plant alcohol, thereby reducing the cholesterol (LDL-C)level.This mechanism has made Yibaiba an important position in blood lipid regulation [1].
Yiju Mai Bu can be used alone, but also often combined with Histen drugs or non -Nobeltter to play a synergistic role, accelerate the improvement of patients heart function, shorten the rehabilitation cycle [2].
Reasonable grasp of the indicator [3]
1, originality : As auxiliary therapy other than diet control, it can be combined with individual or with hydroxyticotrase enzyme A.Sexual or non-family) hypertrophy, which can reduce total cholesterol (TC), LDL-C, and lipoprotein B.
2. HOFH: combined with statins, which can be used as auxiliary therapy for other lipids (such asLDL-C plasma separation replacement method), or when other lipid-lowering therapy is invalid, is used to reduce the level of TC and LDL-C in HOFH patients.
3. Pure componental glycol alcohol (or plant hyperthyrium): Auxiliary therapy other than diet control is used to reduce the family natureGenols and plant melloxy levels of patients with glycol alcohol.
用药注意这4点
（1）可在一天之内任何时间服用，可空腹Or take at the same time as food.
(2) When combining medication with bile acid chelating agent, you should take the Yipan wheat cloth tablets before taking the bile acid chelating agent or after taking ≥ 4 hours.
(3) In the process of receiving the treatment of this product, patients should insist on proper low -fat diet and moderate exercise.
(4) In the control study of the joint application of Yibu Maibu and Jibin, it was found that the continuity of serum aminotransferase increased (≥3 times normal upper limit).Therefore, when the Embroba is combined with the Jiemai Maibu and his class, the liver function determination should be performed before treatment.
Be careful!
Bette: CurrentlyThe security and effectiveness of the combined application of Yibu and other Bette -based Bett -based Bett -category have not been established. Therefore, these two drugs are not recommended (except for Nobelnut).
Circus: Be careful when using cyclopanicinYixuanmaibu.Patients who are combined with erythrobatin and cyclopylasia should monitor the concentration of cycloidin.
Anticoagulant: Forest, other fragrant beanol anticoagulants or fluoropromalone are used, the international standardization ratio (INR) should be appropriately monitored.
Summary:
As an effective tool for cholesterol management, Mcwabs unique mechanism and extensive indication certificate provide new choices for clinical blood lipid management.However, reasonable application and close monitoring are still the key to ensuring safety and effective treatment.notStrong> Medical Doctors Station "Exic programs All
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Summary; more medication areas, continue to update ING, so stay tuned)References:
[1] Boutari C, Karagiannis A, Athyros v G.ROSUVASTATIN and EZETIMIBE for the Treatment of Dyslipidemia and HyperChole Ways, Expert Rev Cardiovasc, 2021, 19 (7): 575-580.
[2] Han Liping. Introcoma combined with Histen drugs on patients with blood lipid metabolism and heart function indicators [J]. Journal of Henan Workers Medical College, 2019, 031 (002): 138-141.
[3] Drug Information: Yichang wheat cloth tablets, MSD PHARMA (Singapore) pte.ltd. State medicine accurate word hj20160181; Chinese medicine quasi -word HJ20171017; 2021/01/06.
