*For medical professionals for reading reference
The medical communitys transnational dialogue, pioneering Develop the perspective of "holographic".
November is the follow -up month of the international lung cancer. Among them, it is designated as an international lung cancer day.The understanding of lung cancer promotes the prevention of lung cancer prevention, early diagnosis and treatment.In order to seek further mutual recognition of the development of China-US lung cancer research and explore the opportunities of cooperation in the Sino-American medical community, the director of the University of Chicago Medical Center, 2021-2022 The United States Clinical Society (ASCO) Chairman of the Society Everett EProfessor Vokes visited China.
On this opportunity, the medical community dialogue with Professor Evertt E. Vokes, share the latest research progress in the field of international lung cancer, spread the views of top scholars on cutting -edge treatment methods to help the public moreI know this important health issue.
Two Milestone Progress Progress in the field of lung cancer:
Target therapy, immunotherapy
In recent years, with the continuous innovation of treatment methods, lung cancer treatment patterns have also undergone tremendous changes.Among them, the research and development and exploration of the two treatment methods of targeted therapy and immunotherapy can be described as a milestone in the transformation of lung cancer treatment.In the 1920s, Professor Tony MOK team of the Chinese University of Hong Kong discovered that the first generation of EGFR-TKI Gefitinib therapy had a prominent effect on patients with EGFR mutations.For the first time for the first time, it reached 1 year.Since then, other mutant sites such as KRAS, ALK, ROS1 have been discovered one after another, genetic testing has become an important and conventional diagnostic method, and corresponding targeted therapy has been rapidly developed and put into use.
In this regard, Professor Vokes said: "Recently, our research team has reported the latest research data of Lolki (ALK-TKI).Patients with lung cancer have no progressive survival (MPFS) for about 5 years.Non -smokers, and the proportion of lung cancer patients with no history of smoke in China is higher than that of international levels.The answers that have a good grade, but they perform mediocre in patients with negative patients who drive gene mutations.As a result, the second milestone progress in the field of lung cancer is the emergence of immunotherapy.
Professor Vokes concluded: "At the moment, lung cancer is no longer regarded as a single disease.Installation has become an important part of the diagnosis of lung cancer. These testing methods determine the choice of further treatment schemes, including the combination of targeting drugs and immunotherapy and multiple therapies.Strong> Three major elements to promote lung cancer treatment:
behavioral education, early screening and environmental improvement
Professor VOKES believes that in the global public, the best way to effectively prevent and diagnose early diagnosis of tumors from the perspective of the overall population is the following two points:The most important thing for public consciousness is called to resist smoking.Quit smoking is one of the few proven effects in the prevention of lung cancer prevention.Studies have shown that quitting smoking is a real benefit for heart health, but the benefits of lung health are reflected in a delay benefit. Long -term observation and research has confirmed that the risk of lung cancer has fallen significantly after quitting smoking.Therefore, quitting smoking is the primary task.Secondly, it is an important aspect of dissuading indoor smoking and avoiding the harm of second -hand smoke from being harmed by second -hand smoke.In addition, the focus of public education is the young people.Medical workers and media need to let more young people understand and accept such a concept: smoking is not a "cool trend", but a "harmful threat".It is necessary to continue to implement the smoking resistance operation. It will shape, deepen, and consolidate the concept of smoking quitting among young people from generation to generation, and make it an effective weapon for lung cancer prevention.
Secondly, for people with a history of smoking, as early as possible, lung cancer screening should be the focus of targeted propaganda.The lung CT can help early detection of lung cancer before symptoms (such as cough and hemoptysis).Of course, due to the more expensive price, the current coverage and availability of CT are limited. Therefore, in the field of lung cancer, the best and most effective health promotion methods are still promoting smoking.
Another factor is public health intervention measures beyond the scope of personal control.A study initiated by Professor Charles Swanton at the Francis Crick Institute, London, England, showed that the incidence and pollution of lung cancer in people without smoking are correlated. Long -term exposure in an environmental environment may cause non -smokingHe suffers from lung cancer.In addition, Professor Charles Swanton also reported the possible mechanism behind this correlation. In short, pollution caused inflammation to induce lung cancer.Although there are still some controversy in the theory of causality, most people in the global medical community have supported the concept of "improving the environment for the promotion of lung health".
The inexhaustible motivation of contemporary scientific research development:
Multi -dimensional dialogue cooperation
The current global lung cancer research organization, including the International Society of Lonopolic Cancer (ISLC), the European Cancer Internal Science Society (ESMO), the American Clinical Oncology Society (ASCO), etc., is the world for the world.Researchers within the scope provide a platform for dialogue and communication, which means more exchanges and cooperation to promote the research and practice of lung cancer globally.Professor Vokes mentioned that the identity of Chairman ASCO is of great significance to him: "This provides me with an opportunity, and one can introduce the latest progress in the treatment of lung cancer in the international field in the speech of the chairman and promote international exchanges."
Taking the rapid progress of Chinas lung cancer research in recent years, Professor Vokes believes: "Patients with positive gene mutations in lung cancer patients in China are higher than that of Western countries. This is Chinas lung cancer research.In the field of new drug research and development and research and development of drug resistance mechanisms, in fact, Chinese scientists have made many contributions in this area."
Finally, as an elite scholar of cancer research, as an excellent team leader, Professor VOKES sends young scholars and regards exchanges and cooperation as an indispensable growth of young people.Opportunity: "I think that in the process of the growth of young researchers, one of the most important activation points lies in the guidance of the instructor. With the help of the mentor, young people have the opportunity to connect with more senior researchers and scientists."
In general, information exchange is the driving force for scientific development.Including young scholars, researchers need to continue to participate in each dimension of multi -form, interdisciplinary, and Vietnamese borders.Cooperation and other forms of exchanges are carried out to carry out cross -disciplinary associations including surgery, radiology, and oncology.Actively promote the cooperation with laboratories in different countries and regions, so that interaction and exchanges have become the melody that runs through scientific research.
Expert Introduction
Professor
Medical Doctor, Professor of Radio and Cell Oncology, Director of the Medical Center of the University of Chicago University, and Director of Biological Sciences.
Experts in the internationally renowned head and neck and lung cancer, in the field of clinical and conversion research on head -neck cancer and lung cancer, the interaction of chemotherapy and radiotherapy.His research shows that combined with the strengthening of radiotherapy and chemotherapy can control local advanced head and neck cancer and increase the survival rate.His research direction in lung cancer is to find new active therapeutic agents, as well as the interaction of chemotherapy and radiotherapy.Cancer Scope commented on it: combining radiotherapy and chemotherapy as a pioneer in the treatment of first -line head -neck cancer.
Dr. Vokes led many professional teams in the field of hematology/oncology. Its outstanding work has made it the winner of many awards and titles, including the newly established transformation research in ASCO in 2008One of the two winners of the professor, one of the winners of the upper respiratory tract malignant tumor studies funded by the Francis L. Lederer Foundation, a member of the United States Clinical Investigation Society and the United States Professor Association (AAP), and selected by the cancer industry publisher in 2013"Cancer Nursing Great Man", 2021 -2022 ASCO Chairman.He has published more than 450 papers and more than 80 works. He has worked in multiple consulting committees, review teams, and many journals, including Journal of Clinical Oncology, Annals of oncology, Clinical LUNG, and InveStIgature. New drags, etc.
Source of this article: Cancer Channel of the Medical Circle
Responsible editor: Wenhui
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