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Professor Xu Zhi talked about minimally invasive discretion: the future direction of precision treatment of lung cancer

2024-11-03 19:11:25

*Only for medical professionals to read reference

Together with Professor Xu Zhi, Xinqiao Hospital of the Army Military Medical University, see those things of lung cancer ablation.Intersection

With the influence of multiple factors such as air pollution, occupational exposure, and smoking, the incidence of respiratory diseases in my country has remained high all year round, becoming a major threat to public health, which challenge.As a comprehensive diagnosis and treatment center for respiratory diseases in Chongqing, the respiratory and crisis medical center of Xinqiao Hospital of the Army Military Medical University has continued to make breakthroughs in disease diagnosis and treatment, scientific research and innovation, and talent training. Especially in the field of lung cancer treatment, it has gradually formed ablation.Technical special minimally invasive treatment methods, provide more accurate and effective treatment plans for the majority of patients.In this regard, the "medical community" specially invites Professor Professor Xu Zhi, Director of Breathe and Critical Medicine Center of Xinqiao Hospital, And clinical experience to readers.

From scientific research teaching to clinical practice: Multiple advantages of Xinqiao Hospitals breathing and criticalized medical centers

Xinqiao Hospital Breathing and Cridual Medicine Center is a collection of medical care,The comprehensive medical center that integrates scientific research and teaching, has a number of key specialty qualifications recognized by the country and military.As the first batch of national key disciplines, national respiratory major continuing education bases, and the entire armys respiratory research institutes, the center is also the national PCCM demonstration unit and training base.The chairman of the respiratory disease alliance undertakes the precise prevention and control tasks of Chongqings heavy respiratory diseases.At present, the center has the research room of respiratory, intensive medical department and field scientific research room, equipped with 181 beds, 9 clinics, and 3 specialist inspection units, and has a professional team of more than 160 people.Among them, high -level talents include 8 professors, 11 associate professors, 7 doctoral supervisors, and 8 master mentors.

In many years of development, the center has gradually formed five major advantages, covering comprehensive treatment of critical respiratory, chronic airway diseases, individualization of lung cancer, complex lung infections and lung intervention in the intervention of lungsfield.Especially in terms of lung cancer diagnosis and treatment, the center is at the forefront of Chongqing, taking the lead in carrying out targeted therapy and immunotherapy, and improved the diagnosis rate of lung cancer and the quality of life of patients through a variety of advanced technologies. Professor Xu Zhi pointed out as a unit that carried out the basic research of respiratory diseases earlier in China, the center focused on focusing on dangerous respiratory, asthma, slow lung block, lung cancer, and lung infection.Fully, cooperated with other units to study the results many times in international medical issues such as "Liu Ye Dao" and "New England Medical Magazine", and have obtained more than 200 national and provincial and ministerial projects.A total of 36 science and technology progress awards.

Precision positioning and individualized therapy: the characteristics of different ablation technologies and indications

About lung tumorDiplide technology, Professor Xu Zhi introduced that currently commonly used ablation technologies in clinical practice include radio frequency ablation (RFA), microwave ablation (MWA), and frozen ablation.RFA is the first armal melting technology for lung tumors. The principle is to insert radio frequency electrodes in tumor tissue and apply transformation current to increase local tissue temperature to 90 ° CThis technology has rich experience and has been widely verified.MWA is an increasingly mature technology. The electromagnetic microwave directly acts on the tumor tissue, which makes the temperature rise rapidly to 60-150 ° C. It is suitable for treating tumors close to large blood vessels.Frozen ablation alternate the frozen tumor cells through extremely low temperature, resulting in cracking necrosis, and at the same time prompts an anti -tumor immune response, and can monitor the treatment effect through CT or MRI.

During the technical implementation process, precise puncture positioning is the key to ablation treatment. The most commonly used metering pest image guidance technology is CT scan.If the tumor is near the chest wall and can display the complete lesion through ultrasound, you can also choose ultrasound guidance.When the lesion is approaching the important structure or the tumor cannot be completely removed after opening the chest, it can also be adjusted under the thoracoscopy.In recent years, the application of new technologies such as electromagnetic navigation bronchoscopy has effectively improved the accuracy and safety of operation. At the same time, the application of puncture robots in lung tumor ablation has gradually matured.

In terms of indication, according to the "Guidelines for Clinical Practical Practice of Performance and metastatic pulmonary tumor (2022)" according to the "video guidance under video guidance", ablation therapy can be divided into cureAnd patent two modes.Healing ablation is mainly suitable for patients who cannot tolerate surgical or radiotherapy, as well as cases of local recurrence after surgery or after radiotherapy, especially early (NSCLC) and multiple primary NSCLC patients.However, it is also required that the maximum diameter of the tumor does not exceed 3 cm and there is no distant metastasis.In contrast, the goal of palliative ablation is to relieve symptoms and improve the quality of life. The indications usually need to be determined by multi -disciplinary consultation (MDT) discussions.For the case where the maximum diameter of the tumor exceeds 5 cm or the number of unilateral pulmonary lesions exceeds 3 (more than 5 bilateral lungs), multi -needle, multi -point, or sub -treatment can be used, or the ablation technology is combined with other treatment methods.In addition, the taboos of ablation therapy include severe lung diseases such as severe coagulation dysfunction, pulmonary fibrosis and other basic diseases, as well as uncontrolled infections and malignant thoracic effusion.It is worth noting that patients with pacemakers are not suitable for RFA treatment.

Micro -invasive concept and patient management: Coordinated to improve the treatment experience of patients with lung cancer

After many years of clinical practiceXinqiao Hospitals breathing and critical condition center has also formed many unique advantages in the application of ablation technology. Professor Xu Zhi said that as early as 2018, its team carried out the first NSCLC ablation treatment.Today, the focus of the centers research and practice has expanded to many aspects such as precise positioning, minimally invasive therapy, extensive application and significant efficacy.In terms of accurate positioning, the center is currently introducing technologies such as puncture robots, robotic pipe mirrors, and electromagnetic navigation punctures to achieve high -efficiency and accurate puncture on tumors, and minimize damage to normal tissues around.At the same time, the minimally invasive characteristics of ablation technology make it compared to traditional surgery, with small trauma, fast recovery, and mild pain. It can optimize the treatment experience of patients. It is particularly suitable for patients who are not tolerated or refused to undergo surgery.In addition, for patients with multiple or relapsed lung cancer, ablation technology also provides a effective local treatment option. In the right case, ablation therapy is expected to achieve local control effects similar to surgery, helping to relieve patients symptoms, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control, control,Cancer pain.

In the actual operation, Professor Xu Zhi believes that pre -surgery evaluation is important, and the patients medical history, physical examination and imaging data are requiredComprehensively evaluate to ensure the adaptability of surgery.During surgery, it can achieve accurate positioning of tumors through CT guidance or puncture robotic guidance, thereby improving the treatment effect.At the same time, it is necessary to choose the most suitable ablation method according to the specific situation of the patient, such as the RFA, MWA, and frozen ablation mentioned in the above.During the operation, we also need to strictly abide by the surgical operation specifications to ensure the safety of surgery and protect the integrity of the surrounding normal tissues.At the level of patients, education must be done before surgery to allow patients to fully understand the process and expected results.After surgery, the condition should be closely monitored, the possible complications that may occur in time, and provide patients with personalized rehabilitation guidance to help them recover as soon as possible.In addition, regular follow -up can effectively track the treatment effect and rehabilitation progress, thereby further improving the long -term quality of survival of patients.

Expert Introduction

Professor Xu Zhi

The Director of the Institute of Breathing and Critical Medicine Center of the Second Affiliated Hospital of the Army Military Medical University

Chief Physician, Chief Physician,Professor, doctoral supervisor, post -doctoral cooperative supervisor, and aesthetic scholar

The Ministry of Educations national key discipline academic leader, western talents

The entire army clinicalKey college academic leader Director of the Key Laboratory of Precision Diagnosis and Treatment of Chongqing Heavier Respiratory Diseases

Chongqing Yingcai (innovative leader), Chongqing academic technology leader

Woning the Second Prize of Chongqing Natural Sciences

Member of the Criminals of the Chinese Medical Association Respiratory Disease Branch

Member of the Continuing Education Group of the Chinese Physician Association

Deputy Chairman of the China Lung Cancer Prevention and Treatment Alliance Immunotherapy Committee

China Anti -Cancer Association Tumor Breathing BranchStanding Committee

Deputy Chairman of the Chongqing Medical Association bacterial infection and drug resistance branch

Long

Deputy Chairman of the Youth Committee of the Chinese Peoples Liberation Army Respiratory Department

For more than 20 years engaged in respiratory medical education and research, we have rich clinical experience, especially for early diagnosis of lung cancer, individualized comprehensive treatment, rescue of patients with severe respiratory, and respiratory intervention diagnosis and treatmentDeep accomplishments.He has participated in many domestic and international military guards.In 2020 and 2022, they participated in the military support of the Wuhan and Shanghai New Crown Extraordnance Medical Team.Mainly engaged in the study and clinical transformation of the pathogenesis and prevention strategies of

Wonderful information is waiting for you

Reference :

[1] YE X, FAN W, WANG Z, et al. Clinical Practice Guidelines on Image-GUIDED THERMAL ABLEON of Primary and Metastatic Lung Tumors (2022 ED ITION).; 18 (5): 1213-1230.

* This article is only used to provide scientific information to medical people, does not represent the viewpoint of this platform

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