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Angdan Silqiong and methaloticamine are commonly used spit drugs for clinical clinical. So what is the difference between the two?How to choose in clinical use?This article is compared with the mechanisms and clinical applications of the two. Lets look at it together!
1. Grasp the indication certificate and be vigilant!
Table 1. Drug difference between Angdan Jiong and metharine
Prescription challenge!
Case information: Male, 89 years old, has medical history.
Diagnostic: gastroesophageal reflux disease
Prescription: omeprazole entericoline tablet for oral 20 mg BID; metharocopyamine tablets;Oral 10mg TID
Analysis: There are two unreasonable medications there, which are ... poke me to read the answer
Two twoKeep your attention to take care of it!
▌ Ang 琼
①When using other drugs (ozine, metharine, fluoroprimidol), or patients with potential arrhythmia risks, ECG monitoring should be strengthened.
② Single intravenous injection dose limit ≤16 mg, prohibited from use with Apotorine, and Time will reduce its blood concentration.
▌ metharocopramine
①Drugs should be fully evaluated when used.
② Be careful with other drugs with dopamine receptors.
③ ECG monitoring should be strengthened with the use of drugs that extend the QT interval.
④ A central nervous suppression may occur, and there are risk of falling (such as elderly, fatigue, and weakness) patients with caution.
⑤ Monitor the condition of muscle tension.[1]
How to deal with excessive drugs?
Angdan Siqiong
Pediatric patients have reported reports of 5-hydroxylidine syndrome (more than 5 mg/kg than estimated intake).Angan Silin hydrochloride has no special effect detoxification drugs, and proper support treatment should be given to patients.Patients need supportive treatment, including intubation, usually fully recovered within 1-2 days, without sequelae [2].
▌ metharocopramine
The symptoms of excessive drugs may include sleepiness, Direct disorder and tainers reactions.Antidine or anti -Parkinson disease or anti -choline -resistant anti -group amine drugs may help control the exterior reaction of the cone.Symptoms are self -limiting and usually disappear within 24h.
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References:
, China Anti -Cancer Association Cancer Supporting and Treatment Professional Committee. China on the Consensus on Nausea and Vomiting Prevention and Treatment of Cancer drugs (2022 edition) [J]. Chinese Medical Journal, 2022, 102 (39): 15.Doi: 10.3760/CMA.J.cn112137-20220810-01724.
[2] ProductInformation: ZofranDanSetronhydroChyLorides. 21.04.
