People with diabetes merged , the first choice of three types of antihypertensive drugs .These three types of antihypertensive drugs are: "Pully", Vascular tensionin converting enzyme inhibitors; "Satan", Vascular Tension Anti -antagonist; Salabaquan Salin, Shatakus Alizan, Vascular tensional receptor encephalin enzyme suppressionPreparation .These three types of drugs have the effects of inhibitory and blocking nephrotidin-vascular tension system. They belong to the same large category, so they are also called renin-vascular tension system inhibitors.Of course, the third category of Shakubaqu has the effect of inhibiting brain crypse, and one more target!
Say Preferred three categories, not three categories, Class .
Say The first choice of these three categories, it is not only one of these three types of medicines, but also Use .
Why do these three types of antihypertensive drugs be preferred for hypertension of diabetes?
Because these three types of medicines can inhibit renin-vascular tension system !
We know that this kidney-vascular tension system is particularly active in patients with hypertension, such as high blood pressure, kidney damage, myocardial hypertrophy, arteriosclerosis, etc.Related.Among people with diabetes, type 2 diabetes of our adults all have insulin resistance, so the insulin in the body will be excessive secretion, forming high insulin ledmia.One of the bad things of this high insulin ledmia is to activate the renin-vascular tension system.Therefore, the hypertension of diabetes, this renin-vascular tension system is particularly active (why can blood sugar lowering the blood sugar lower blood pressure lower blood pressure?).Therefore, for the hypertension of diabetes, these three categories of these three categories that can inhibit nephrotin-vascular tension systems are targeted and directly hit targets.And such as diabetes and hypertension can cause kidney damage and develop proteinuria. These three types of drugs can reduce the pressure in kidney glomerular balls, protect kidney, and reduce proteinuria.
Preferred three types of medicines, of course, are not three types of use at the same time. Choose one category.
These three types of medicines, "Puli" category is to inhibit vascular tensioning enzymes. This target is more upstream in the system; "Satan" is to inhibitThe receptor of vascular tension is at the end of the system.All acts on the same system, the combined effect will be affected, and similar side effects will be added.What about Sakubabequan Salin?With Tasartan or Alicedam, it is naturally not suitable for "Puli" or "Satan".Besides, the combination of Shakabaqu and "Puli" drugs will also increase the risk of vascular neuropathy. Not only cannot it be used, but also taboos. When the two drugs need to be replaced, it must be separated by 36 hours.Intersection
Preferred three types of medicines are not only one of these three types of medicines.Anti -suppressive drug.
The three types of drugs are preferred are proposed based on the characteristics of patients with diabetes with hypertension patients.The first choice is to choose one of these three types of drugs when choosing an antihypertensive drug, but if two, three or more antihypertensive drugs are required, it is possible, and should be with other antihypertensive reduction.The medicine is united, and the combination of medication is quite a lot.Because the hypertension of people with diabetes, especially the hypertension of proteinuria, blood pressure is best controlled lower, below 130/80mmHg.Note that the proteinuria here, In the early days, it was trace albuminuria. This is not a routine to be tested. It is a urine test that requires separate urine .
The most commonly used combinations of these three types of drugs are and "horizontal" antihypertensive drug combination ;The second is the combination of and thiazide diuretics .The united preparations with diuretics, the "Satan" category, such as glutamine, chlorodattium chlorodrazodiazine, hobesartanine chloride, chloroholine oligrazine, osalite hydrochloride, and so on.If you encounter high blood pressure with fast heart rate, you can also and the β -blocking agent of the "Lore" category .It is even more beneficial to patients with diabetic vascular disease.
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